What techniques can be used to disrupt (re)consolidation? Can “lost” memories be recovered?
RATS AND RECONSOLIDATION
Our rat lab examines these questions of consolidation, reconsolidation, and retrieval using rats and human participants. Researchers in our rat lab use appetitively-motivated tasks that require rats to dig for buried sweet cereal rewards (i.e., “Froot Loops” cereal). We employ pharmacological agents (e.g., protein synthesis inhibitors and beta-adrenergic receptor antagonists) to disrupt (re)consolidation in our rat model.
DECLARATIVE MEMORY AND DISTRACTION
Researchers in our human memory lab employ a variety of appetitive tasks that measure not only declarative (conscious) memory (i.e., episodic and semantic memory), but also nondeclarative (nonconscious) memory (e.g., physiological responses). We examine a variety of visuospatial, tactile, and meditation-based methods for interrupting (re)consolidation. The ultimate goal of our lab is to apply our work to aspects of treatment for memory-based forms of human psychopathology (e.g., depression and anxiety).